Properties
Description
DBCO-xylan conjugation represents a cyclooctyne-containing hybrid combining copper-free click chemistry potential with xylan's β-1,4-xylose scaffold. The system demonstrates improved azide conjugation efficiency through strain-promoted cycloaddition.
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-diphenylcyclooctyne can be used for its potential to analyze glucose-binding kinetics in boronic acid-functionalized sensing materials.