Dacarbazine, soluble in warmed DMSO, warmed water and warmed ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA-RNA synthesis.
Molecular Weight
182.18
Molecular Formula
C6H10N6O
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 12 mg/mL (65.86 mM); Water (warmed): 2 mg/mL (10.97 mM); Ethanol (warmed): 1 mg/mL (5.48 mM); In vivo: 0.5% CMC Na, 28 mg/mL
Applications
Dacarbazine is a DNA damage inhibitor that plays a key role in adding alkyl groups to DNA, leading to cross-linking and preventing DNA replication, thereby inducing cancer cell death.
Publications
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Publications
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