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Docetaxel (DTX) and ammonium bicarbonate (ABC) co-loaded thermosensitive liposomes
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Cat. No.: X26-05-ZQ2832

Docetaxel (DTX) and ammonium bicarbonate (ABC) co-loaded thermosensitive liposomes

Synonym: DTX/ABC co-loaded TSLs; Docetaxel-ammonium bicarbonate co-loaded thermosensitive liposomes; DTX/ABC co-encapsulated thermosensitive LPs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly advanced multi-functional responsive material features docetaxel and ammonium bicarbonate co-loaded thermosensitive liposomes. The structural matrix incorporates a phase-transition lipid base composed primarily of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine designed to undergo a sharp melting transition at a specific thermal threshold (41ºC), co-encapsulating the highly hydrophobic taxane derivative docetaxel (DTX) within its lipid bilayer shell alongside the gas-generating salt ammonium bicarbonate (ABC) entirely within its central aqueous core. This specific configuration couples a thermally triggered release mechanism with an acoustic or mechanical disruption handle (via rapid thermal generation of carbon dioxide gas bubbles across the phase boundary), completely preventing taxane crystallization and physical vesicle aggregation under baseline laboratory calibration indices.
Source
Custom synthesis
Functional Group
Docetaxel; Ammonium bicarbonate; Thermosensitive matrix
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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