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DOPC phospholipid-modified cholesterol liposomes
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Cat. No.: X26-05-ZQ2560

DOPC phospholipid-modified cholesterol liposomes

Synonym: DOPC/Chol liposomes; DOPC-modified cholesterol LPs; DOPC cholesterol lipid vesicles

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This high-purity synthetic model formulation features 1,2-dioleoyl-sn-glycero-3-phosphocholine blank liposomes modified with a precise molecular fraction of sterols (DOPC phospholipid-modified cholesterol liposomes). The vesicular matrix self-assembles from a detailed molecular blend of the highly fluid monounsaturated lipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and high-purity cholesterol without containing active drug cargo. The integration of sterol molecules into the highly fluid, cis-kinked C18 oleoyl bilayer core restricts hydrocarbon tail mobility, creating localized liquid-ordered domains and modulating passive membrane permeability without inducing crystallographic phase separation.
Source
Custom synthesis
Functional Group
DOPC; Cholesterol
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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