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DOPC:Chol:DOPG:DOPE-PEG(2000) (60:30:5:5) liposomes
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Cat. No.: X26-05-ZQ1817

DOPC:Chol:DOPG:DOPE-PEG(2000) (60:30:5:5) liposomes

Synonym: DOPC/Chol/DOPG/DOPE-PEG2000 (60:30:5:5) LPs; DOPC:Chol:DOPG:DOPE-PEG2000 60:30:5:5 liposomes; DOPC-Chol-DOPG-DOPE-PEG2000 60:30:5:5 LPs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly complex, multi-component formulation features dioleoylphosphatidylcholine (DOPC), cholesterol (Chol), dioleoylphosphatidylglycerol (DOPG), and dioleoylphosphatidylethanolamine-polyethylene glycol(2000) [DOPE-PEG(2000)] in a precise 60:30:5:5 molar ratio. The structural architecture combines a fluid neutral matrix base (DOPC) with a fluidity modulator (cholesterol), an anionic lipid component (5 mol% DOPG) to introduce a defined negative surface charge profile, and a pegylated lipid conjugate (5 mol% DOPE-PEG) to construct a hydrophilic outer stealth steric layer. This detailed molecular assembly creates a stable, negatively charged surface topography that precisely balances electrostatic repulsion and steric stabilization, preventing physical vesicle aggregation.
Source
Custom synthesis
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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