Lentinan-dioleoylphosphatidylethanolamine, termed DOPE-lentinan, constitutes a contemporary biochemical fusion combining the immune-regulatory β-1,3-1,6-glucan lentinan with DOPE. The hybrid compound utilizes lentinan's triple-coil geometry and cancer-restraining potential via thymus-mediated immunological stimulation processes.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
DOPE
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-dioleoylphosphatidylethanolamine can be used for its potential to design DOPE-coupled systems for endosomal escape enhancement during gene editing tool delivery.
Publications
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Publications
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