This xylan-DOTA derivative merges macrocyclic chelator functionality with hemicellulose-derived polysaccharide chemistry, where the branched xylan framework provides multiple conjugation sites while maintaining aqueous dispersibility through hydroxyl-rich surface topology.
Glycan Name
Xylan
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
DOTA
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid can be used for its potential to design macrocyclic chelators for radiometal complexation in molecular imaging probe development.
Publications
Publications (0)
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Publications
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