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This highly responsive formulation features doxorubicin-loaded dual-sensitive liposome nanogels (DOX@pH/R-lipogels) designed with an environmental-responsive hydrogel-lipid hybrid core-shell architecture. The internal core structure encapsulates hydrophilic doxorubicin (DOX) hydrochloride within a cross-linked polymer hydrogel network engineered to disassemble under specific pH variations and reducing environments, which is completely enclosed by a high-purity phospholipid bilayer shell. When exposed to an acidic or reducing laboratory buffer assay, the internal hydrogel and surrounding lipid matrix undergo a coordinated conformational breakdown, triggering accelerated cargo release. This advanced configuration provides a precise analytical model for studying dual-stimulus triggered mass transport phenomena.
Source
Custom synthesis
Functional Group
Doxorubicin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)
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Publications
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CD BioGlyco is a leading biotechnology company specializing in glycobiology. We deliver high-quality products and services to support cutting-edge research worldwide.