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DSPE-PEG(2000)-OCT containing doxorubicin stealth liposomes

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Cat. No.: X26-05-ZQ1581

DSPE-PEG(2000)-OCT containing doxorubicin stealth liposomes

Name: DSPE-PEG(2000)-OCT containing doxorubicin stealth liposomes
SKU: X26-05-ZQ1581

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Synonym: DSPE-PEG2000-OCT doxorubicin stealth liposomes; OCT-modified DSPE-PEG2000 DOX stealth LPs; Octreotide-targeted DSPE-PEG2000 doxorubicin liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly engineered delivery system features distearoylphosphatidylethanolamine-polyethylene glycol(2000)-octreotide containing doxorubicin stealth liposomes [DSPE-PEG(2000)-OCT containing doxorubicin stealth liposomes]. The vesicle architecture utilizes a rigid lipid bilayer that encapsulates hydrophilic doxorubicin hydrochloride within its acidic core via an ammonium sulfate gradient, while the outer surface is functionalized with octreotide (OCT) cyclic peptide targeting ligands covalently linked to distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-PEG(2000)) polymer anchors. This structural configuration creates a dense hydrophilic layer that prevents vesicle aggregation and limits drug leakage while presenting the cyclic peptide array for advanced surface-binding evaluations. The resulting vesicles exhibit high colloidal stability and a highly uniform spherical morphology.

Source

Custom synthesis

Functional Group

DSPE-PEG2000; Octreotide; Doxorubicin

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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