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This highly complex material comprises dual-functional chromium-doped zinc gallogermanate near-infrared persistent luminescence nanoparticles conjugated with aptamers and encapsulated within alendronate-modified liposomes (ZGGO:Cr-Apt@Lip-AL nanoprobes). The structural matrix features a robust phospholipid vesicle shell modified with surface-bound bone-targeting alendronate (AL) molecules, which encapsulates pre-formed chromium-doped zinc gallogermanate (Zn3Ga2GeO8:Cr3+ or ZGGO:Cr) persistent luminescence nanodots that are covalently functionalized with synthetic oligonucleotidic aptamers (Apt). This advanced hybrid configuration pairs long-lasting, excitation-free optical emission with a multi-functionalized target modeling surface. The resulting nanoprobes exhibit high physical stability against cargo leakage and gravitational sedimentation in laboratory test setups.
Source
Custom synthesis
Functional Group
ZGGO:Cr; Aptamer
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)
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Publications
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