IU1-47 targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis. It targets UCH-L1, UCH-L1, and UCH-L3.
IU1-47 is a DUB inhibitor, similar to IU1, used in research to elucidate the functions of USP14 in protein degradation pathways.
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