Cat. No.: X24-06-ZQ866
DUB inhibitor P 22077, Purity ≥98%
Synonym: 1247819-59-5; DUB inhibitor; P22077
- MDL: MFCD22580421
- CAS Number: 1247819-59-5
- Compound CID: 46931953
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
P 22077, soluble in DMSO and insoluble in ethanol and water, targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis. It targets USP2core, USP47, Calpain1, CathepsinD, CT-L, DEN1, JOSD2, MMP13, PLA2, Plpro, and SENP6core.
Molecular Formula
C12H7F2NO3S2
Targets
USP2core: >50 μM (EC50); USP47: 8.74 μM (EC50); Calpain1: >50 μM (EC50); CathepsinD: >50 μM (EC50); CT-L: >50 μM (EC50); DEN1: >50 μM (EC50); JOSD2: >50 μM (EC50); MMP13: >50 μM (EC50); PLA2: >50 μM (EC50); Plpro: >50 μM (EC50); SENP6core: >50 μM (EC50)
Solubility
DMSO: 57 mg/mL (180.76 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
P 22077 is a DUB inhibitor that targets the protease USP7, crucial for research in cancer and immune response regulation.
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