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DUB inhibitor P005091, Purity ≥98%
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Cat. No.: X24-06-ZQ867

DUB inhibitor P005091, Purity ≥98%

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Synonym: 882257-11-6; DUB inhibitor; P5091

  • MDL: MFCD00123202
  • CAS Number: 882257-11-6
  • Compound CID: 2819993
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
P005091, soluble in DMSO and insoluble in ethanol and water, targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis. It targets Calpain1, MMP13, Caspase-3, CathepsinD, CathepsinK, EKL, PLA2, UCH-L1, USP15, USP20, and USP21.
Molecular Weight
348.22
Molecular Formula
C12H7Cl2NO3S2
Targets
Calpain 1: >100 μM (EC50); MMP13: >100 μM (EC50); Caspase-3: >100 μM (EC50); CathepsinD: >100 μM (EC50); CathepsinK: >100 μM (EC50); EKL: >100 μM (EC50); PLA2: >100 μM (EC50); UCH-L1: >100 μM (EC50); USP15: >100 μM (EC50); USP20: >100 μM (EC50); USP21: >100 μM (EC50)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 28 mg/mL (80.4 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
P005091 is a DUB inhibitor used to investigate its role in the ubiquitin-proteasome system, focusing on immune and cancer-related applications.
Publications
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