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DYRK inhibitor AZ191, Purity ≥98%
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Cat. No.: X24-05-ZQ934

DYRK inhibitor AZ191, Purity ≥98%

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Synonym: 1594092-37-1; AZ 191; AZ-191; DYRK inhibitor

  • CAS Number: 1594092-37-1
  • Compound CID: 72716071
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZ191, soluble in DMSO and ethanol and insoluble in water, is designed to block the activity of dual-specificity tyrosine-regulated kinase (DYRK), which are involved in various cellular processes including cell differentiation and survival. It targets DYRK1A, Dyrk1B, and DYRK2.
Molecular Weight
429.52
Molecular Formula
C24H27N7O
Targets
DYRK1A: 88 nM; Dyrk1B: 17 nM; DYRK2: 1890 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (188.58 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.32 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ191 can be used to inhibit KRAS interactions specifically, investigated in cancer progression.
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