NSC697923, soluble in DMSO and insoluble in ethanol and water, targets the E2 enzymes involved in the ubiquitin-proteasome pathway, aiming to modulate protein degradation processes that are critical for various cellular functions and implicated in numerous diseases. It targets E2 complex Ubc13-Uev1A.
NSC697923 is an E2 conjugating inhibitor used to examine its impact on the ubiquitin-conjugating enzyme Ubc13, relevant in inflammation studies.
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