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Cat. No.: X24-06-ZQ875

E3 ligase inhibitor TAME, Purity ≥98%

Synonym: 901-47-3; E3 ligase inhibitor

  • CAS Number: 901-47-3
  • Compound CID: 1550286
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
TAME, soluble in DMSO, water and ethanol, modulates the activity of E3 ubiquitin ligases, which play a critical role in targeting specific proteins for ubiquitination and subsequent degradation by the proteasome. It targets APC.
Molecular Weight
342.42
Molecular Formula
C14H22N4O4S
Targets
APC
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 68 mg/mL (198.59 mM); Water: 68 mg/mL (198.59 mM); Ethanol: 3 mg/mL (8.76 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAME is an E3 ligase inhibitor used for investigating the degradation of cyclin-dependent kinase inhibitors, relevant in cancer research.
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