Cat. No.: X24-06-ZQ875
E3 ligase inhibitor TAME, Purity ≥98%
Synonym: 901-47-3; E3 ligase inhibitor
- CAS Number: 901-47-3
- Compound CID: 1550286
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
TAME, soluble in DMSO, water and ethanol, modulates the activity of E3 ubiquitin ligases, which play a critical role in targeting specific proteins for ubiquitination and subsequent degradation by the proteasome. It targets APC.
Molecular Formula
C14H22N4O4S
Solubility
DMSO: 68 mg/mL (198.59 mM); Water: 68 mg/mL (198.59 mM); Ethanol: 3 mg/mL (8.76 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAME is an E3 ligase inhibitor used for investigating the degradation of cyclin-dependent kinase inhibitors, relevant in cancer research.
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