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Epigenetic reader domain inhibitor ABBV-744, Purity ≥98%
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Cat. No.: X24-05-ZQ412

Epigenetic reader domain inhibitor ABBV-744, Purity ≥98%

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Synonym: 2138861-99-9; ABBV 744; ABBV744; Epigenetic reader domain inhibitor

  • CAS Number: 2138861-99-9
  • Compound CID: 132010322
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Product Size
2 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ABBV-744, soluble in DMSO and insoluble in ethanol and water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2 (BD2), BRD3 (BD2), BRD4 (BD2), BRD4 (BD2), and BRDT (BD2).
Molecular Weight
491.55
Molecular Formula
C28H30FN3O4
Targets
BRD2 (BD2): 8 nM; BRD3 (BD2): 13 nM; BRD4 (BD2): 4 nM; BRD4 (BD2): 3 nM; BRDT (BD2): 18 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 94 mg/mL (191.22 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ABBV-744 is utilized to study the selective inhibition of the BET family of bromodomains, particularly in the context of therapeutic applications in cancer.
Publications
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