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Epigenetic reader domain inhibitor CF53, Purity ≥98%
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Cat. No.: X24-05-ZQ436

Epigenetic reader domain inhibitor CF53, Purity ≥98%

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Synonym: 1808160-52-2; CF 53; CF-53; Epigenetic reader domain inhibitor

  • CAS Number: 1808160-52-2
  • Compound CID: 118340554
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CF53 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2-BD1, BRD2 (BD2), BRD3 (BD1), BRD3 (BD2), BRD4 (BD1), BRD4 (BD1), BRD4 (BD1), BRD4 (BD2), BRDT (BD1), BRDT (BD2), and CECR2.
Molecular Weight
443.51
Molecular Formula
C24H25N7O2
Targets
BRD2-BD1: 1.1 nM (Kd); BRD2 (BD2): 0.6 nM (Kd); BRD3 (BD1): 0.52 nM (Kd); BRD3 (BD2): 0.49 nM (Kd); BRD4 (BD1): <1 nM (Ki); BRD4 (BD1): 2 nM; BRD4 (BD1): 2.2 nM (Kd); BRD4 (BD2): 0.8 nM (Kd); BRDT (BD1): 2 nM (Kd); BRDT (BD2): 1 nM (Kd); CECR2: 570 nM (Kd)
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
CF53 can be used to research the inhibition of the BET family of proteins in cancer therapy.
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