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Epigenetic reader domain inhibitor dBET57, Purity ≥98%
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Cat. No.: X24-05-ZQ442

Epigenetic reader domain inhibitor dBET57, Purity ≥98%

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Synonym: 1883863-52-2; dBET 57; dBET-57; Epigenetic reader domain inhibitor

  • CAS Number: 1883863-52-2
  • Compound CID: 118912822
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
dBET57, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD4 (BD1).
Molecular Weight
699.18
Molecular Formula
C34H31ClN8O5S
Targets
BRD4 (BD1): 500 nM (DC50)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 89 mg/mL (127.29 mM); Water: Insoluble; Ethanol: 11 mg/mL (15.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
dBET57 can be used to investigate targeted protein degradation strategies for BET proteins in cancer research.
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