Epigenetic reader domain inhibitor GS-626510, Purity ≥98%

Synonym: 1637770-13-8; GS626510; GS 626510; Epigenetic reader domain inhibitor

CAS Number: 1637770-13-8
Compound CID: 86301666

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

MSDS

Properties

Description

GS-626510 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BD1, BD2, BRD2, BRD3, and BRD4.

Molecular Weight

394.47

Molecular Formula

C₂₅H₂₂N₄O

Targets

BD1: 83 nM; BD2: 78 nM; BRD2: 0.59-2.5 nM (Kd); BRD3: 0.65-0.66 nM (Kd); BRD4: 1.3-3.2 nM (Kd)

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

GS-626510 can be used in research focused on inhibiting the bromodomain-containing protein 4 (BRD4) in diseases like cancer.