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Epigenetic reader domain inhibitor HJB-97, Purity ≥98%
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Cat. No.: X24-05-ZQ458

Epigenetic reader domain inhibitor HJB-97, Purity ≥98%

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Synonym: 2093391-24-1; HJB 97; HJB97; Epigenetic reader domain inhibitor

  • CAS Number: 2093391-24-1
  • Compound CID: 135397673
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
HJB-97 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2-BD1, BRD2 BD1, BRD2 BD2, BRD2 BD2, BRD3 BD1, BRD3 BD1, BRD3 BD2, BRD3 BD2, BRD4 BD1, BRD4 BD1, and BRD4 BD2.
Molecular Weight
500.56
Molecular Formula
C26H28N8O3
Targets
BRD2-BD1: 0.9±0.2 nM (Ki); BRD2 BD1: 3.1±0.7 nM; BRD2 BD2: 0.27±0.09 nM (Ki); BRD2 BD2: 3.9±0.5 nM; BRD3 BD1: 0.18±0.01 nM (Ki); BRD3 BD1: 0.18±0.01 nM (Ki); BRD3 BD2: 0.21±0.03 nM (Ki); BRD3 BD2: 1.9±0.4 nM; BRD4 BD1: 0.5±0.2 nM (Ki); BRD4 BD1: 7.0±0.6 nM; BRD4 BD2: 1.0±0.1 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
HJB-97 can be used to study molecular mechanisms related to BET (Bromodomain and Extra-Terminal) family proteins.
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