Properties
Description
I-BRD9, soluble in DMSO and insoluble in ethanol and water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD4 and BRD9.
Molecular Formula
C22H22F3N3O3S2
Targets
BRD4: 5.3 (pIC50); BRD9: 7.3(pIC50)
Solubility
DMSO: 94 mg/mL (188.92 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
I-BRD9 is used to investigate the role of the BRD9 bromodomain in gene regulation and chromatin remodeling.
