Epigenetic reader domain inhibitor OTX015, Purity ≥98%

Synonym: 202590-98-5; OTX 015; OTX-015; Epigenetic reader domain inhibitor

CAS Number: 202590-98-5
Compound CID: 9936746

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

OTX015, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRDs.

Molecular Weight

491.99

Molecular Formula

C₂₅H₂₂ClN₅O₂S

Targets

BRDs: 10-19 nM (EC₅₀)

Form

Lyophilized powder

Purity

Solubility

DMSO: 89 mg/mL (180.9 mM); Water: Insoluble; Ethanol: 89 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

OTX015 is used to study BET bromodomain inhibitors in pre-clinical cancer models.