Etoposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double-stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. This product can be used for research in the fields of medicine and pharmacy.
Molecular Weight
588.56
Molecular Formula
C29H32O13
Form
Powder
Purity
≥98%, determined by HPLC.
Identity
Confirmed by MS and NMR.
Applications
Etoposide can be used for research in the fields of medicine and pharmacy.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
Publications
Publications (0)
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Publications
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