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Folate and indocyanine green/rapamycin co-loaded targeted long-circulating thermosensitive liposomes (FA-ICG/RAPA-TSLs)

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Cat. No.: X26-05-ZQ2823

Folate and indocyanine green/rapamycin co-loaded targeted long-circulating thermosensitive liposomes (FA-ICG/RAPA-TSLs)

Name: Folate and indocyanine green/rapamycin co-loaded targeted long-circulating thermosensitive liposomes (FA-ICG/RAPA-TSLs)
SKU: X26-05-ZQ2823

Inquiry

Synonym: FA-ICG/RAPA-TSLs; Folate-targeted ICG/rapamycin stealth TSLs; FA-targeted ICG/RAPA long-circulating thermosensitive liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced multi-functional responsive material features folate functionalized long-circulating thermosensitive liposomes co-loaded with indocyanine green and rapamycin (FA-ICG/RAPA-TSLs). The intricate structural framework incorporates a phase-transition lipid base composed primarily of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine designed to undergo a sharp melting transition at a specific thermal threshold, co-encapsulating the near-infrared tricarboxylic dye indocyanine green (ICG) and the hydrophobic macrolide rapamycin (RAPA) within its dual-phase core domains, while its exterior boundary is surface-modified with folate (FA) ligands linked via polymer anchors. This complex layout couples a thermally triggered release mechanism and a target-mimetic array with high-intensity near-infrared optical tracking handles, completely preventing macrolide crystallization and physical vesicle aggregation under baseline laboratory calibration indices.

Source

Custom synthesis

Functional Group

Folate; Indocyanine green; Rapamycin; Thermosensitive matrix

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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