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Folate-magnetic dual-targeted doxorubicin-loaded phase-transition liposome nanoparticles (FA-PFH-Fe3O4@ADM)

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Cat. No.: X26-05-ZQ1546

Folate-magnetic dual-targeted doxorubicin-loaded phase-transition liposome nanoparticles (FA-PFH-Fe3O4@ADM)

Name: Folate-magnetic dual-targeted doxorubicin-loaded phase-transition liposome nanoparticles (FA-PFH-Fe 3 O 4 @ADM)
SKU: X26-05-ZQ1546

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Synonym: Folate-magnetic dual-targeted DOX phase-transition LPs; FA-magnetic doxorubicin phase-transition liposomal NPs; FA-PFH-Fe3O4@ADM

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced material comprises folate and magnetic dual-targeted doxorubicin-loaded perfluorohexane phase-transition liposome nanoparticles (FA-PFH-Fe3O4@ADM). The complex internal architecture features an emulsion of volatile liquid perfluorohexane (PFH) along with hydrophilic doxorubicin hydrochloride (adriamycin/ADM) and superparamagnetic iron oxide (Fe3O4) nanoparticles encapsulated within a lipid vesicle shell, whose exterior surface is functionalized with folate (FA) ligands. When exposed to an external alternating magnetic field or acoustic stress in a laboratory assay, the magnetic nanoparticles generate localized heat that triggers a liquid-to-gas phase transition of the perfluorohexane core. This internal vaporization creates intense localized pressure that mechanically ruptures the lipid bilayer, providing a multi-responsive model for studying targeted, stimulus-induced burst-release mass transport phenomena.

Source

Custom synthesis

Functional Group

Folate; Magnetic component; Doxorubicin; Perfluorohexane

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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