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Folate, PEG and HSA-modified IAL targeted long-circulating liposomes

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Cat. No.: X26-05-ZQ1580

Folate, PEG and HSA-modified IAL targeted long-circulating liposomes

Name: Folate, PEG and HSA-modified IAL targeted long-circulating liposomes
SKU: X26-05-ZQ1580

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Synonym: Folate/PEG/HSA modified IAL targeted long-circulating liposomes; FA-PEG-HSA modified IAL stealth LPs; Folate-PEG-HSA targeted IAL long-circulating liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly complex material comprises folate, polyethylene glycol, and human serum albumin co-modified isoalantolactone loaded targeted long-circulating liposomes. The structural matrix incorporates the hydrophobic sesquiterpene lactone isoalantolactone (IAL) within the hydrocarbon domain of a stable phospholipid bilayer, while the external boundary is multi-functionalized with folate ligands, polyethylene glycol (PEG) chains, and human serum albumin (HSA) proteins linked via polymer-lipid anchors. This advanced configuration introduces a highly complex macromolecular surface topography paired with a sterically stabilized core, preventing the rapid crystallographic precipitation of the sesquiterpene lactone cargo in open suspension. The resulting multi-modified vesicles exhibit high colloidal stability and a highly uniform spherical morphology.

Source

Custom synthesis

Functional Group

Folate; HSA; Isoalantolactone

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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