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Folate-PEG-liposome/vincristine (FA-PEG-LPs/VCR)

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Cat. No.: X26-05-ZQ1585

Folate-PEG-liposome/vincristine (FA-PEG-LPs/VCR)

Name: Folate-PEG-liposome/vincristine (FA-PEG-LPs/VCR)
SKU: X26-05-ZQ1585

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Synonym: Folate-PEG-liposomal vincristine; FA-PEG-LPs/VCR complexes; FA-PEG-LPs/VCR

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This engineered delivery system features folate and polyethylene glycol co-modified vincristine loaded liposomes (FA-PEG-LPs/VCR). The vesicle architecture utilizes a rigid lipid bilayer that encapsulates the hydrophilic bisindole alkaloid vincristine (VCR) sulfate within its acidic core via a transmembrane ion gradient, while the outer surface is functionalized with folate (FA) targeting ligands covalently linked to polyethylene glycol (PEG) polymer-lipid anchors. This structural configuration creates a dense hydrophilic steric layer that prevents vesicle aggregation and isolates the active core while presenting the folate ligand array for advanced surface-binding evaluations. The resulting vesicles exhibit high colloidal stability and a highly uniform spherical morphology.

Source

Custom synthesis

Functional Group

Folate; Vincristine

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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