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Folate receptor-binding ligand Folata-PEG-CHEMS-modified liposomes
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Cat. No.: X26-05-ZQ2233

Folate receptor-binding ligand Folata-PEG-CHEMS-modified liposomes

Synonym: Folate-PEG-CHEMS modified liposomes; Folate receptor-targeted Folate-PEG-CHEMS LPs; Folate-PEG-CHEMS LPs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This advanced engineered smart liposome system features folate-modified cholesteryl hemisuccinate pH-responsive liposomes (Folate receptor-binding ligand Folate-PEG-CHEMS-modified liposomes). The structural framework utilizes a pH-sensitive lipid base incorporating cholesteryl hemisuccinate (CHEMS) that alters its molecular packing in response to environmental hydrogen ion variations, whose outer surface is dual-modified with folate targeting ligands linked via polyethylene glycol (PEG) polymer anchors. This dual-functional configuration balances a dense target-mimetic ligand array with a protective steric shield, completely preventing physical vesicle aggregation below the transition threshold while providing a sharp pH-responsive mass transfer switch.
Source
Custom synthesis
Functional Group
Folate-CHEMS
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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