Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate, and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma Apoptosis. This product can be used for research in the fields of medicine and pharmacy.
Molecular Weight
514.65
Molecular Formula
C30H40O7
Source
Ganoderma lucidum
Form
White powder
Purity
≥98%, determined by HPLC.
Solubility
It is soluble in chloroform and methanol.
Identity
Confirmed by MS and NMR.
Applications
Ganoderic acid D can be used for research in the fields of medicine and pharmacy.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
Publications
Publications (0)
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Publications
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