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This advanced formulation features gadolinium-diethylenetriaminepentaacetic acid encapsulated glucose-modified long-circulating liposomes (Gd-DTPA-encapsulated glucose-modified long-circulating liposomes) designed with a glycosylated sterically stabilized affinity surface. The vesicle architecture utilizes a stable phospholipid bilayer that encapsulates the water-soluble contrast agent gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) within its central aqueous core, while the outer surface is functionalized with glucose molecules covalently linked to polyethylene glycol polymer-lipid anchors. This structural configuration creates a dense hydrophilic carbohydrate layer that prevents vesicle aggregation and minimizes passive contrast agent leakage across the lipid membrane. The resulting nanoliposomes exhibit a highly uniform spherical morphology and serve as a precise model for studying glycosylated transport systems.
Source
Custom synthesis
Functional Group
Gd-DTPA; Glucose
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)
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Publications
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CD BioGlyco is a leading biotechnology company specializing in glycobiology. We deliver high-quality products and services to support cutting-edge research worldwide.