The xylan-glycyrrhetinic acid complex combines bioactive elements of this triterpenoid with xylan's carbohydrate architecture, leveraging the polysaccharide's inherent biocompatibility to optimize dissolution characteristics through its branching β-1,4-xylose chain network.
Glycan Name
Xylan
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Glycyrrhetinic acid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-glycyrrhetinic acid can be used for its potential to target hepatic stellate cells using triterpenoid-modified carriers in liver fibrosis models.
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Publications
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