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Glycyrrhetinic acid (GA)-targeted doxorubicin liposomes (GA-DOX-LPs)

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Cat. No.: X26-05-ZQ2828

Glycyrrhetinic acid (GA)-targeted doxorubicin liposomes (GA-DOX-LPs)

Name: Glycyrrhetinic acid (GA)-targeted doxorubicin liposomes (GA-DOX-LPs)
SKU: X26-05-ZQ2828

Inquiry

Synonym: GA-DOX-LPs; Glycyrrhetinic acid-targeted doxorubicin liposomes; GA-targeted DOX liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This advanced engineered system features glycyrrhetinic acid functionalized and doxorubicin loaded liposomes (GA-DOX-LPs). The structural matrix encapsulates the hydrophilic anthracycline doxorubicin (DOX) entirely within its central aqueous core via an active remote-loading ammonium sulfate matrix, while its exterior lipid bilayer boundary is surface-modified with specific pentacyclic triterpenoid glycyrrhetinic acid (GA) targeting ligands linked via covalent lipid anchors. This precise configuration coordinates an active remote-loading anthracycline matrix with a dense target-mimetic ligand array, altering overall surface hydration parameters to completely prevent physical vesicle aggregation while restricting passive drug leakage under ambient laboratory conditions.

Source

Custom synthesis

Functional Group

Glycyrrhetinic acid (GA); Doxorubicin

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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