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Glycyrrhetinic acid-modified docetaxel liposomes

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Cat. No.: X26-05-ZQ2830

Glycyrrhetinic acid-modified docetaxel liposomes

Name: Glycyrrhetinic acid-modified docetaxel liposomes
SKU: X26-05-ZQ2830

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Synonym: GA-modified DTX liposomes; Glycyrrhetinic acid-modified docetaxel LPs; GA-functionalized docetaxel liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This advanced engineered system features glycyrrhetinic acid functionalized and docetaxel loaded liposomes. The structural matrix incorporates the highly hydrophobic taxane derivative docetaxel directly within the lipophilic hydrocarbon tail domains of its bilayer shell, whose exterior boundary is surface-modified with specific pentacyclic triterpenoid glycyrrhetinic acid targeting ligands linked via covalent lipid anchors. This precise configuration coordinates a dense target-mimetic ligand array with an optimized taxane matrix, altering the natural lateral lipid packing constraints to completely prevent physical vesicle aggregation while completely suppressing docetaxel crystallization or rapid phase separation in open laboratory testing media.

Source

Custom synthesis

Functional Group

Glycyrrhetinic acid (GA); Docetaxel

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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