Cat. No.: X24-05-ZQ253
GSK-3 inhibitor AZD1080, Purity ≥98%
Synonym: 612487-72-6; AZD 1080; AZD-1080; GSK-3 inhibitor
- CAS Number: 612487-72-6
- Compound CID: 135564570
Product Size
5 mg; 10 mg; 25 mg; 50 mg
Properties
Description
AZD1080, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets GSK-3α and GSK-3β.
Molecular Formula
C19H18N4O2
Targets
GSK-3α: 6.9 nM; GSK-3β: 31 nM
Solubility
DMSO: 49 mg/mL (146.54 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD1080 is used to investigate its effects on GSK-3 inhibition in Alzheimer's disease.
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