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Guanabenz acetate

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Cat. No.: X23-12-YM805

Guanabenz acetate

Synonym: 23256-50-0; Wytensin; WY-8678 acetate

CAS Number: 23256-50-0
Compound CID: 5702062

Product Size

100 mg; 200 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

Guanabenz acetate, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α2a-adrenergic receptor, α2b-adrenergic receptor, and α2c-adrenergic receptor.

Molecular Weight

291.13

Molecular Formula

C₁₀H₁₂Cl₂N₄O₂

Targets

α2A-adrenergic receptor: 8.25 (pEC₅₀); α2B-adrenergic receptor: 7.01 (pEC₅₀); α2C-adrenergic receptor: <5 (pEC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 56 mg/mL (192.35 mM); Water: insoluble; Ethanol: 5 mg/mL (17.17 mM)

Applications

Guanabenz acetate can be used for its calming effect on certain parts of the brain involved in migraine pathophysiology, potentially reducing the frequency and severity of migraine attacks.

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