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HDAC inhibitor Domatinostat, Purity ≥98%
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Cat. No.: X23-10-ZQ278

HDAC inhibitor Domatinostat, Purity ≥98%

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Synonym: 910462-43-0; Domatinostat; 4SC-202; 4SC-202 (free base); (E)-N-(2-Aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide; HDAC inhibitor

  • CAS Number: 910462-43-0
  • Compound CID: 15985904
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Domatinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, and HDAC3.
Molecular Weight
447.51
Molecular Formula
C23H21N5O3S
Targets
HDAC1: 1.20 μM; HDAC2: 1.12 μM; HDAC3: 0.57 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 77 mg/mL (172.06 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Domatinostat is studied for its ability to selectively inhibit class I HDACs, contributing to research on its application in cancer treatment.
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