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HDAC inhibitor Droxinostat, Purity ≥98%
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Cat. No.: X23-10-ZQ279

HDAC inhibitor Droxinostat, Purity ≥98%

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Synonym: 99873-43-5; Droxinostat; 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide; HDAC inhibitor

  • CAS Number: 99873-43-5
  • Compound CID: 568416
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Droxinostat, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9.
Molecular Weight
243.7
Molecular Formula
C11H14ClNO3
Targets
HDAC1: >20 μM; HDAC10: >20 μM; HDAC2: >20 μM; HDAC3: 16.9 μM; HDAC4: >20 μM; HDAC5: >20 μM; HDAC6: 2.47 μM; HDAC7: >20 μM; HDAC8: 1.46 μM; HDAC9: >20 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 47 mg/mL (192.86 mM); Water: Insoluble; Ethanol: 47 mg/mL (192.86 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Droxinostat is employed to investigate its inhibitory effects on HDAC6 and HDAC8, supporting research into its potential therapeutic applications in cancer and neurodegenerative diseases.
Publications
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