Cat. No.: X23-10-ZQ275
HDAC inhibitor Fimepinostat, Purity ≥98%
Synonym: 1339928-25-4; CUDC-907; Fimepinostat; CUDC 907; CUDC907; PI3K/HDAC Inhibitor; Fimepinostat [USAN]; HDAC inhibitor
- MDL: MFCD22420823
- CAS Number: 1339928-25-4
- Compound CID: 54575456
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Fimepinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9.
Molecular Formula
C23H24N8O4S
Targets
HDAC1: 1.7 nM; HDAC10: 2.8 nM; HDAC11: 5.4 nM; HDAC2: 5.0 nM; HDAC3: 1.8 nM; HDAC4: 409 nM; HDAC5: 674 nM; HDAC6: 27 nM; HDAC7: 426 nM; HDAC8: 191 nM; HDAC9: 554 nM
Solubility
DMSO: 87 mg/mL (171.07 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Fimepinostat is applied in studies to assess its dual inhibition of HDACs and phosphoinositide 3-kinase (PI3K) as a strategy for treating various cancers.
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