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HDAC inhibitor ITF2357 (Givinostat), Purity ≥98%
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Cat. No.: X23-10-ZQ290

HDAC inhibitor ITF2357 (Givinostat), Purity ≥98%

Synonym: 732302-99-7; Givinostat hydrochloride monohydrate; ITF2357; Givinostat (ITF2357); ITF2357 (Givinostat); Givinostat hydrochloride hydrate; (6-((Diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride hydrate; HDAC inhibitor

  • MDL: MFCD28502062
  • CAS Number: 732302-99-7
  • Compound CID: 9804991
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
ITF2357 (Givinostat), soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HD1-B, HD1-B, and HD1-A.
Molecular Weight
476
Molecular Formula
C24H27N3O4.HCl.H2O
Targets
HD1-B: 7.5 nM; HD1-B: 10 nM; HD1-A: 16 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 94 mg/mL (197.49 mM); Water: Insoluble; Ethanol: 3 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
ITF2357 (Givinostat) is researched for its broad-spectrum HDAC inhibitory effects and therapeutic applications, particularly in cancer and inflammatory disease contexts.
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