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HDAC inhibitor Tubastatin A HCl, Purity ≥98%
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Cat. No.: X23-10-ZQ347

HDAC inhibitor Tubastatin A HCl, Purity ≥98%

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Synonym: Tubastatin A hydrochloride; Tubastatin A HCl; 1310693-92-5; Tubastatin A (Hydrochloride); UHCM2AYJVX; TSA HCl; N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide; HDAC inhibitor

  • MDL: MFCD20488052
  • CAS Number: 1310693-92-5, 1239262-52-2
  • Compound CID: 57336514
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Tubastatin A HCl, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC8, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, and HDAC7.
Molecular Weight
371.9
Molecular Formula
C20H21N3O2.HCl
Targets
HDAC1: 16.4 μM; HDAC8: 854 μM; HDAC10: >30 μM; HDAC11: >30 μM; HDAC2: >30 μM; HDAC3: >30 μM; HDAC4: >30 μM; HDAC5: >30 μM; HDAC6: 15 nM; HDAC7: >30 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 67 mg/mL (180.17 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tubastatin A HCl is employed to explore selective HDAC6 inhibition and its effects on neurodegeneration, inflammation, and cancer.
Publications
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