HIV protease inhibitor ABX-464, Purity ≥98%

Synonym: 1258453-75-6; HIV protease inhibitor; ABX464; ABX 464; SPL-464; SPL464; SPL 464

CAS Number: 1258453-75-6
Compound CID: 49846599

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

ABX-464, soluble in DMSO and ethanol and insoluble in water, blocks the protease enzyme, essential for the maturation and replication of HIV, playing a key role in highly active antiretroviral therapy (HAART). It targets HIV-1.

Molecular Weight

338.71

Molecular Formula

C₁₆H₁₀ClF₃N₂O

Targets

HIV-1: 0.1-0.5 μM (IC₅₀, in PBMCs)

Form

Lyophilized powder

Purity

Solubility

DMSO: 58 mg/mL (171.24 mM); Water: Insoluble; Ethanol: 58 mg/mL (171.24 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

ABX-464 is explored in HIV research for its ability to inhibit HIV replication through impact on RNA splicing, offering insights into novel antiretroviral therapy approaches.