Properties
Description
Pepstatin A, soluble in DMSO and warmed ethanol and insoluble in water, blocks the protease enzyme, essential for the maturation and replication of HIV, playing a key role in highly active antiretroviral therapy (HAART). It targets aspartic protease.
Molecular Formula
C34H63N5O9
Targets
Aspartic protease
Solubility
DMSO: 51 mg/mL (74.35 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL (1.45 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pepstatin A is utilized to investigate its role in inhibiting HIV protease, contributing to the development of antiviral treatments.