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HMT inhibitor 3-Deazaneplanocin A HCl, Purity ≥98%
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Cat. No.: X24-05-ZQ491

HMT inhibitor 3-Deazaneplanocin A HCl, Purity ≥98%

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Synonym: 120964-45-6; DZNep; NSC 617989; DZNep HCl; Histone methyltransferase inhibitor

  • CAS Number: 120964-45-6
  • Compound CID: 14563109
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Product Size
2 mg; 5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
3-Deazaneplanocin A HCl, soluble in DMSO and water and insoluble in ethanol, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets S-adenosylhomocysteine hydrolase.
Molecular Weight
298.73
Molecular Formula
C12H15ClN4O3
Targets
S-adenosylhomocysteine hydrolase (): 50 pM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 49 mg/mL (164.03 mM); Water: 49 mg/mL (164.03 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
3-Deazaneplanocin A HCl is used to study the inhibition of histone methyltransferases like EZH2 in epigenetic regulation.
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