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HSP inhibitor, KOS953, Purity ≥98%
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Cat. No.: X24-09-YM061

HSP inhibitor, KOS953, Purity ≥98%

Synonym: 75747-14-7; Tanespimycin; NSC330507; CP 127374; KOS-953; KOS 953; [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-Hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate; HSP inhibitor

  • MDL: MFCD04973892
  • CAS Number: 75747-14-7
  • Compound CID: 6505803
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Product Size
10 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
MSDS
Properties
Description
KOS953, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 585.7, and its molecular formula is C31H43N3O8. It targets the HSP90 (Cell-free assay).
Molecular Weight
585.7
Molecular Formula
C31H43N3O8
Targets
HSP90 (Cell-free assay)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 97 mg/mL (165.61 mM); Water: insoluble; Ethanol: 5 mg/mL; In vivo: 9 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
KOS953 plays a key role in modulating gene expression involved in cancer development and progression by targeting epigenetic regulators.
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