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Hydroxycamptothecin (HCPT) chitosan hydrochloride (CS-HCl)-coated nanoliposomes

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Cat. No.: X26-05-ZQ1850

Hydroxycamptothecin (HCPT) chitosan hydrochloride (CS-HCl)-coated nanoliposomes

Name: Hydroxycamptothecin (HCPT) chitosan hydrochloride (CS-HCl)-coated nanoliposomes
SKU: X26-05-ZQ1850

Inquiry

Synonym: HCPT chitosan hydrochloride NLs; CS-HCl coated hydroxycamptothecin nanoliposomes; HCPT CS-HCl NLs

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This advanced composite formulation features hydroxycamptothecin-loaded chitosan hydrochloride-coated nanoliposomes (Hydroxycamptothecin (HCPT) chitosan hydrochloride (CS-HCl)-coated nanoliposomes). The structural framework consists of a high-purity phospholipid vesicle core encapsulating the hydrophobic quinoline alkaloid hydroxycamptothecin (HCPT), whose exterior boundary is completely enveloped by an electrostatically bound outer layer of the water-soluble polymer chitosan hydrochloride (CS-HCl). The amine groups of the chitosan coating introduce a highly positive surface charge profile and establish a dense hydrophilic steric layer around the lipid headgroups, which increases membrane thickness and protects the active lactone ring from premature hydrolytic opening.

Source

Custom synthesis

Functional Group

Hydroxycamptothecin; Chitosan hydrochloride

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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