Lentinan-OH, referred to as hydroxyl-lentinan, constitutes a newly formulated conjugate combining the immune-adjusting β-1,3-1,6-glucan lentinan with hydroxyl. The synthesized structure employs lentinan's triplex helical geometry and malignancy-restraining attributes via thymus-mediated immune system activation pathways.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Hydroxyl
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-OH can be used for its potential to modify hydroxyl groups for PEGylation strategies to improve blood circulation half-life.
Publications
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Publications
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