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IAP antagonist LCL-161, Purity ≥98%
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Cat. No.: X23-10-ZQ114

IAP antagonist LCL-161, Purity ≥98%

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Synonym: 1005342-46-0; LCL161; LCL-161; (S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide; IAP antagonist

  • MDL: MFCD23160049
  • CAS Number: 1005342-46-0
  • Compound CID: 24737642
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LCL-161, soluble in DMSO and warmed ethanol and insoluble in water, is a molecule designed to neutralize the function of IAPs, thereby promoting apoptosis, especially in cancer cells. It targets cIAP and XIAP.
Molecular Weight
500.2
Molecular Formula
C26H33FN4O3S
Targets
cIAP; XIAP
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (171.78 mM); Water: Insoluble; Warmed ethanol: 17 mg/mL (33.95 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LCL-161 is investigated for its potential to degrade IAPs and induce apoptosis in cancer therapy research.
Publications
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