Lentinan-indocyanine green, designated ICG-lentinan, comprises a modern bioconjugate coupling the immunotherapeutic β-1,3-1,6-glucan lentinan with ICG. This amalgamated entity employs lentinan's three-dimensional helical geometry and tumor-inhibitory properties through thymus-mediated immune activation pathways.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
ICG
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-indocyanine green can be used for its potential to explore ICG conjugates for real-time surgical guidance visualization in preclinical tumor resection models.
Publications
Publications (0)
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Publications
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