Inquiry
Cat. No.: X23-10-ZQ588
IL receptor inhibitor SC-144, Purity ≥98%
Synonym: 895158-95-9; SC144; N'-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)pyrazine-2-carbohydrazidE; SC 144; SC-144; IL receptor inhibitor
- MDL: MFCD25976763
- CAS Number: 895158-95-9
- Compound CID: 400169
Properties
Description
SC-144, soluble in DMSO and insoluble in ethanol and water, blocks the binding of interleukins (cytokines) to their corresponding receptors on the cell surface, thereby inhibiting the downstream signaling pathways. It targets gp130.
Molecular Weight
322.3
Molecular Formula
C16H11FN6O
Targets
gp130
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 26 mg/mL (80.67 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SC-144 can be used for researching its cytotoxic effects in cancer therapy targeting GP130/STAT3 signaling pathways.
Publications
Publications (0)

×
Publications
Thank you for choosing our products for your research. By sharing your publications or experimental feedback, you provide invaluable insights that help fellow scientists accelerate their discoveries. Your contribution also drives our commitment to continuous product optimization.
As a token of our appreciation, verified submissions will receive an exclusive discount code for your next order.
*Submitted research data and images may be featured on our product pages. We strictly protect your personal privacy; no sensitive contact information will ever be disclosed.
Related Products
- IL receptor inhibitor Suplatast tosilate, Purity ≥98%
- IRAK inhibitor 3, Purity ≥98%
- IL receptor inhibitor Y320, Purity ≥98%
- IL receptor inhibitor MCC950 sodium, Purity ≥98%
- IL receptor inhibitor Apilimod, Purity ≥98%
- IL receptor inhibitor beta-Interleukin I (163-171), Purity ≥98%
Quick Links
PRODUCTS
- Hot Glycans
- Featured Products
- Carbohydrates
- Nucleosides and Nucleotides
- Enzymes
- Lectin Products
- Carbohydrate Antigen
- Glycoconjugates
- Assay Kits
- Glycosylation Related Products
- Natural Products
- Inhibitors
- Protein Tyrosine Kinases
- TGF-β-Smad
- Cell Cycle
- Neuronal Signaling
- Proteases
- Cell Metabolism
- Endocrinology-Hormones
- GPCR-G Protein
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- 5-HT Receptor
- Adenosine Receptor
- Dopamine Receptor
- Neurokinin Receptor
- Calcium-sensing Receptor
- S1P Receptor
- Platelet-activating Factor (PAF) Receptor
- LPA Receptor
- Smoothened Receptor
- Opioid Receptor
- Melatonin Receptor
- CGRP Receptor
- Endothelin Receptor
- Prostanoid Receptor
- Cannabinoid Receptor
- Glucagon Receptor
- G Protein
- Guanylate Cyclase
- Orexin Receptor
- Imidazoline Receptor
- Neurotensin Receptor
- Peptide Receptor
- CCK
- NPY Receptor
- MCHR1 (GPR24)
- Sigma Receptor
- GHSR
- GPCR19
- Formyl Peptide Receptor (FPR)
- Angiotensin Receptors
- GLP-1 receptors
- Rev-Erb Receptors
- CRFR
- Vasopressin Receptor
- Protease-Activated Receptors (PAR)
- Oxytocin Receptor
- Bradykinin Receptor
- Adenylyl Cyclase
- Urotensin Receptor
- Somatostatin Receptors
- Bombesin Receptor
- cAMP
- CXCR
- Leukotriene Receptor
- Membrane Transporters-Ion Channels
- AMPA Receptor
- Sodium Channel
- Calcium Channel
- SGLT
- ATPase
- Proton Pump
- Potassium Channel
- P-gp
- CFTR
- Chloride Channels
- TRPV
- Monocarboxylate Transporters (MCT)
- HCN Channel
- NCX
- TRP Channel
- Na+-H+ Exchanger
- OCT
- Glutamate (EAAT) Transporter
- Serotonin Transporter
- BCRP
- VDAC
- Aquaporin
- Piezo Channel
- Monoamine Transporter
- CRM1
- Transferases
- Stem Cells-Wnt
- Autophagy Signaling
- Metabolism
- MAO
- PPAR
- FXR
- Cytochrome P450
- PDE
- HSP
- Hydroxylase
- Factor Xa
- DHFR
- Dehydrogenases
- Procollagen C-proteinase
- Carbonic Anhydrase
- LXR
- FAAH
- 15-PGDH
- CETP
- Ferroptosis
- HMG-CoA Reductase
- Isocitrate Dehydrogenase (IDH)
- IDO
- Retinoid Receptor
- Lipase
- Phospholipase
- Lipoxygenase
- AhR
- NAMPT
- GLUT
- Antimetabolite
- Hexokinase
- Epoxide Hydrolase
- Stearoyl-CoA Desaturase (SCD)
- Lipid Metabolism
- Neuronal Metabolism
- SREBP
- LDL
- Foxo1
- DGAT
- Farnesyl Transferase
- Thioredoxin
- Vitamin
- Decarboxylase
- ACLY
- Fatty Acid Synthase (FASN)
- Glucokinase
- Lactate Dehydrogenase A (LDHA)
- Oxidative Phosphorylation
- PFKFB3
- Ribonucleotide Reductase
- Acetyl-CoA Carboxylase
- Glucosidase
- PAI-1
- Immunology & Inflammation
- PI3K/Akt/mTOR
- Angiogenesis
- Apoptosis
- DNA Damage
- Epigenetics
- JAK/Stat
- MAPK
- Microbiology
- NF-kB/IkB
- Stem Cells/Wnt
- DNA-RNA Synthesis
- Cytoskeletal Signaling
- Ubiquitin
- Other inhibitors
- PROTAC
- Bioactive Compounds
- Glycobiology Arrays
- Glycolipids
- Nanomaterials
GalNAc-L96 intermediate, T1 (Cat#: X24-11-YM010)
GalNAc-L96 intermediate, T2 (Cat#: X24-11-YM011)
GalNAc-L96 intermediate, T3 (Cat#: X24-11-YM012)
GalNAc-L96 intermediate, T4-Amine (Cat#: X24-11-YM014)
Tri-GalNAc(OAc)3 Cbz (Cat#: X24-11-YM015)
Tri-GalNAc(OAc)3 (Cat#: X24-11-YM016)
Tri-GalNAc(OAc)3 TFA (Cat#: X24-11-YM017)
GalNAc-L96-OH (Cat#: X24-11-YM018)
GalNAc-L96-TEA (Cat#: X24-11-YM019)
Neu5Gcα(2-6)N-Glycan (Cat#: X23-03-YW036)
A2G2 N-Glycan (Cat#: X23-03-YW037)
A2G2S2 N-Glycan (Cat#: X23-03-YW038)
A2 N-Glycan (Cat#: X23-03-YW039)
A2[6]G1 N-Glycan (Cat#: X23-03-YW040)
M3 N-Glycan (Cat#: X23-03-YW041)
A2[3]G2S1 N-Glycan (Cat#: X23-03-YW042)
Core 2 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW178)
Core 2 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW179)
Core 3 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW180)
Core 3 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW181)
Core 4 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW182)
T antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW192)
T antigen O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW193)
Tn antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW194)
Blood group A trisaccharide (Cat#: XCO0060Q)
Blood group B trisaccharide (Cat#: XCO0068Q)
Blood group H disaccharide (Cat#: XCO0074Q)
Lewis A trisaccharide (Cat#: XCO0079Q)
3'-Sulfated lewis A (Cat#: XCO0080Q)
Lewis B tetrasaccharide (Cat#: XCO0083Q)
Lewis X trisaccharide (Cat#: XCO0085Q)
Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Lacto-N-biose (Cat#: XCO0089Q)
2'-Fucosyllactose (Cat#: XCO0091Q)
3-Fucosyllactose (Cat#: XCO0092Q)
Lactodifucotetraose (Cat#: XCO0093Q)
Lacto-N-triose I (Cat#: XCO0094Q)
3'-Sialyllactose sodium salt (Cat#: XCO0096Q)
6'-Sialyllactose sodium salt (Cat#: XCO0098Q)
3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478)
FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480)
TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481)
Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482)
Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598)
Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611)
Heparin disaccharide I-A (Cat#: X22-11-ZQ662)
Chondroitine sulfate (Cat#: X23-04-XQ1118)
GalNAcβ(1-4)GlcNAcβ-Sp3-Biotin (Cat#: X22-12-ZQ005)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-Biotin (Cat#: X22-12-ZQ006)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-FITC (Cat#: X22-12-ZQ007)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA (Cat#: X22-12-ZQ008)
Glcβ(1-4)GalNAcα-Sp3-Biotin (Cat#: X22-12-ZQ037)
Glcβ(1-4)GalNAcα-Sp3-PAA-Biotin (Cat#: X22-12-ZQ038)
Glcβ(1-4)GalNAcα-Sp3-PAA-FITC (Cat#: X22-12-ZQ039)
Glcβ(1-4)GalNAcα-Sp3-PAA (Cat#: X22-12-ZQ040)
GlcCer (d18:1/8:0) (Cat#: X23-11-ZQ101)
GalCer (d18:1/16:0) (Cat#: X23-11-ZQ112)
LacCer (d18:1/8:0) (Cat#: X23-11-ZQ118)
Lc3Cer (d18:1/8:0) (Cat#: X23-11-ZQ131)
Lc4Cer (d18:1/12:0) (Cat#: X23-11-ZQ146)
Sialyl-Lc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ162)
Lewis a Cer (d18:1/16:0) (Cat#: X23-11-ZQ175)
nLc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ190)
Methyl-γ-cyclodextrin (DS 12) (Cat#: X23-11-YM119)
Carboxymethyl-ɑ-cyclodextrin sodium salt (Cat#: X23-11-B003)
Carboxymethyl-γ-cyclodextrin sodium salt (Cat#: X23-11-B004)
Succinyl-ɑ-cyclodextrin (Cat#: X23-11-B005)
Succinyl-γ-cyclodextrin (Cat#: X23-11-B006)
ɑ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B007)
β-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B008)
γ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B009)
Lysine-dextran, MW 4 kDa (Cat#: X22-09-ZQ273)
Phenyl-dextran, MW 150 kDa (Cat#: X22-09-ZQ279)
FITC-Q-dextran, MW 10 kDa (Cat#: X22-09-ZQ280)
FITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ283)
TRITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ287)
FITC-dextran sulfate, MW 10 kDa (Cat#: X22-09-ZQ291)
Dextran amine, MW 20 kDa (Cat#: X22-09-ZQ377)
TRITC-dextran, MW 40 kDa (Cat#: X22-09-ZQ383)
Biotin-dextran-FITC, MW 20 kDa (Cat#: X22-09-ZQ389)
Online Inquiry


